Search results for " Functional MRI"

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The relationship between genetic risk variants with brain structure and function in bipolar disorder: A systematic review of genetic-neuroimaging stu…

2017

Genetic-neuroimaging paradigms could provide insights regarding the pathophysiology of bipolar disorder (BD). Nevertheless, findings have been inconsistent across studies. A systematic review of gene-imaging studies involving individuals with BD was conducted across electronic major databases from inception until January 9th, 2017. Forty-four studies met eligibility criteria (N = 2122 BD participants). Twenty-six gene variants were investigated across candidate gene studies and 4 studies used a genome-wide association approach. Replicated evidence (i.e. in >2 studies) suggests that individuals with BD carrying the BDNF Val66Met risk allele could have reduced hippocampal volumes compared …

Transtorno BipolarCandidate genediffusion tensor imagingvoxel based morphometryBipolar disorderBipolar disorder Genetic polymorphisms Neuroimaging Magnetic resonance imaging Functional MRI Diffusion tensor imagingvoxel based morphometryCognitive NeuroscienceBrain Structure and FunctionGenome-wide association studyNeuroimagingComputational biologyGenetic polymorphismsFaculty of Social Sciences03 medical and health sciencesDISC1Behavioral Neuroscience0302 clinical medicineMagnetic resonance imagingNeuroimaginggenetic polymorphisms/dk/atira/pure/core/keywords/FacultyOfSocialSciencesImatges per ressonància magnèticamedicineHumansManic-depressive illnessANK3Bipolar disorderCervellNeuroimagemDiffusion tensor imagingvoxel based morphometryFunctional MRIGenetic polymorphismneuroimagingTrastorn bipolarbiologyBipolar disorder; Diffusion tensor imagingvoxel based morphometry; Functional MRI; Genetic polymorphisms; Magnetic resonance imaging; Neuroimaging; Neuropsychology and Physiological Psychology; Cognitive Neuroscience; Behavioral NeuroscienceReproducibility of ResultsBrainmedicine.disease030227 psychiatryNeuropsychology and Physiological Psychology5-HTTLPRbiology.proteinfunctional MRIImagem por Ressonância MagnéticaPsychologyNeuroscience030217 neurology & neurosurgeryHumanGenome-Wide Association Study
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Altered functional connectivity in blepharospasm/orofacial dystonia

2017

Abstract Introduction Blepharospasm is characterized by involuntary eyelid spasms. It can be associated with perioral dystonia (Meige's syndrome or orofacial dystonia). We aimed at studying resting‐state functional brain connectivity in these patients and its potential modulation by therapeutic botulinum toxin injections. Methods We performed resting‐state functional MRI and a region of interest‐based analysis of functional connectivity in 13 patients with blepharospasm/Meige's syndrome in comparison to 13 healthy controls. Patients were studied before and 4 weeks after botulinum toxin treatment. Simultaneous facial electromyography was applied to control for involuntary facial movements. R…

Male0301 basic medicineCingulate cortexBotulinum ToxinsBlepharospasmNeurotoxinsBlepharospasmSomatosensory systemMeige's syndrome03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineCortex (anatomy)medicineHumansOriginal ResearchAgedDystoniaBrain MappingElectromyographyPostcentral gyrusbusiness.industryfunctional connectivityBrainMeige's syndromeMiddle Agedmedicine.diseaseMagnetic Resonance ImagingBotulinum toxineye diseasesddc:DystoniaTreatment Outcome030104 developmental biologymedicine.anatomical_structureorofacial dystoniaDystonic DisordersFemaleresting‐state functional MRImedicine.symptombusinessNeuroscience030217 neurology & neurosurgerymedicine.drugBrain and Behavior
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